Draft genomes of three Antarctic Psychrobacter strains producing antimicrobial compounds against Burkholderia cepacia complex, opportunistic human pathogens
Marco Fondi, Valerio Orlandini, Elena Perrin, Isabel Maida, Emanuele Bosi, Maria Cristiana Papaleo,
Luigi Michaud,
Angelina Lo Giudice,
Donatella de Pascale,
Maria Luisa Tutino,
Pietro Liņ,
Renato Fani
Laboratory of Microbial and Molecular Evolution, Department of Biology, University of Florence, Via Madonna del Piano 6, 50019 Sesto Fiorentino, Firenze, Italy.
Abstract
Herein we present the draft genomes of three Psychrobacter strains isolated from Antarctic sponges and able to inhibit the growth of bacteria belonging to the Burkholderia cepacia complex, responsible for infections of the respiratory system in patients affected by Cystic Fibrosis. The comparative analysis of the annotated genomes of these Psychrobacter strains highlighted their differences in terms of overall genomic content (e.g. shared gene sets) and allowed the identification of gene clusters hypothetically involved in the biosynthesis of antimicrobial compounds.
Keywords: Comparative genomics;
Antarctic bacteria;
Genomics;
Burkholderia infections.
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